By J.; Stearns, R. E. Hartmanis
Hartmanis, J.; Stearns, R. E. - Algebraic constitution conception of Sequential Machines Na Angliiskom Iazyke. writer: . yr: 1966. position: . Pages: Hardcover
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More complete characterization of body composition within animal models might provide useful guidance in selecting from a range of possibilities for phenotyping in new studies. For example, rodent models of obesity, physical activity, and carcinogenesis can include detailed phenotyping in experimental studies [137, 59]. Furthermore, transgenic models such as the “fatless” mouse can help determine the contribution of adipose tissue to disease risk . Another powerful tool for exploring effects of obesity on carcinogenesis involves chromosome substitution strains .
Free Radic Biol Med, 40(4): 721–733. 47. Giovannucci E (2003). Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence. J Womens Health (Larchmt ), 12(2):173–182. 48. Giovannucci E, Michaud D (2007). The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas. Gastroenterology, 132(6):2208–2225. 49. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Willett WC (1997). Height, body weight, and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev, 6(8):557–563.
In addition, the limited number of people who are able to achieve sustained weight loss in the current obesogenic environment of the United States and in many countries worldwide may further limit the ability to quantify the influence of weight loss on cancer risk. Further, a randomized control prevention trial of weight loss with cancer as an endpoint is not feasible for several reasons. Strong randomized clinical trial evidence has documented the benefit of weight loss for diabetes, hypertension, and cardiovascular disease.
Algebraic Structure Theory of Sequential Machines by J.; Stearns, R. E. Hartmanis